B12 vitamin

Vitamin B12 acts as a coenzyme for several metabolic functions, including fat and carbohydrate metabolism, as well as protein synthesis.

It is rapidly absorbed by the gastrointestinal tract, mainly in the lower half of the ileum.

The vitamin B12 and IF complex formed passes into the intestine and binds to the receptors of the ileal mucosa, where it is absorbed into the circulation.

It is necessary for growth, cell replication, hematopoiesis (chronic deficiency of this vitamin produces megaloblastic anemia) and the synthesis of nucleoproteins and myelin.


Vitamin B12 (2) contributes:

  • To normal energy metabolism
  • To normal functioning of the nervous system
  • to normal homocysteine ​​metabolism
  • To normal psychological function
  • To normal formation of red blood cells
  • To normal functioning of the immune system
  • To reduce tiredness and fatigue
  • To the process of cell division

Main sources in food

Vitamin B12 (4) found naturally in various foods

  • All foods of animal origin: meat, poultry and especially liver and kidneys.
  • Fish and seafood
  • Dairy products, milk, yogurt, cheese
  • Egg

Suggested daily intake

2.1 μg (6)

Weighted for the Mexican distribution according to the General Census of Population and Housing, 2000.

Nutritional effect of deficiency

Vitamin B12 deficiency causes fatigue, weakness, constipation, loss of appetite, weight loss and megaloblastic anemia.

Alterations of the central and peripheral nervous system, sensory and motor disorders such as numbness and tingling in the hands appear.

Decreased memory and cognitive functions.

Balance problems, depression, confusion, and inflammation of the mouth or tongue.

Bibliographic references:

Drafting. (2021, December 14). Vitamin B12 - ANAISA . ANAISA. https://anaisa.mx/vitamina_b12/
1. Allen L, de Benoist B, Dary O, Hurrell R. (2006). Guidelines on Food Fortification with Micronutrients. Davis, CA, United States of America: Organization of the United Nations.
2. Commission Regulation (EU) No 432|2012 of 16 May 2012 establishing a list of authorized health claims for foods other than those relating to the reduction of the risk of disease and development and the health of children.
3. Regulation of Health Control of Products and Services.
4. NOM-043-SSA2-2012. Basic health services. Promotion and education for health in alimentary matters. Criteria Criteria to provide guidance.
5. Sight and life publication. Vitamins and minerals: A brief guide. Switzerland: Print kompensiert.
6. Bourges, H. Casanueva, E. et al. (2008). Recommendations of ingestion of nutrients for the Mexican population. Mexico: Editorial Panamericana.

1 comment

What is the relationship between vitamin B12 and megaloblastic anemia, and how does vitamin B12 deficiency lead to this condition? Tel U

Teknik Komputer November 06, 2023

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